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BSI BS ISO 21446:2019

Infant formula and adult nutritionals. Determination of <i>trans</i> and total (<i>cis</i> + <i>trans</i>) vitamin K<sub>1</sub> content. Normal phase HPLC
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BSI BS ISO 21446:2019

Infant formula and adult nutritionals. Determination of <i>trans</i> and total (<i>cis</i> + <i>trans</i>) vitamin K<sub>1</sub> content. Normal phase HPLC

PUBLISH DATE 2019
PAGES 26
BSI BS ISO 21446:2019

This document specifies a method for the quantitative determination of trans and total (cis + trans) vitamin K1 in infant, pediatric and adult nutritionals using normal phase (NP) high-performance liquid chromatography (HPLC) with post-column reduction and fluorescence detection. The method demonstrated good linearity over a standard range of ~2 μg/l to 80 μg/l trans vitamin K1, and the limit of quantification (LOQ) was estimated to be 0,4 μg/l for standards and 0,09 μg/100 g ready to feed (RTF) for samples assuming 4 grams of sample are diluted to 10 ml.

SDO BSI: British Standards Institution
Document Number ISO 21446
Publication Date Jan. 9, 2019
Language en - English
Page Count
Revision Level
Supercedes
Committee AW/34
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