Cigarettes. Determination of tobacco specific nitrosamines in mainstream cigarette smoke with an intense smoking regime. Method using LC-MS/MS
This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of cigarette mainstream smoke with the intense smoking regime specified in ISOÂ 20778 by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
| SDO | BSI: British Standards Institution |
| Document Number | ISO 23921 |
| Publication Date | Oct. 1, 2020 |
| Language | en - English |
| Page Count | 24 |
| Revision Level | |
| Supercedes | |
| Committee | AW/40 |
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