ISO 21501-1:2025

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Determination of particle size distribution - Single particle light interaction methods - Part 1: Light scattering aerosol spectrometer

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ISO 21501-1:2025

Determination of particle size distribution - Single particle light interaction methods - Part 1: Light scattering aerosol spectrometer

ISO 21501-1:2025

This document specifies characteristics of a light scattering aerosol spectrometer (LSAS) which is used for measuring the size, number concentration and number-based size distribution of particles suspended in a gas.

This document provides the calibration procedure and the validation method for aerosol spectrometers.

This document applies to:

  • characterization of metered dose inhalers (MDI), dry powder inhalers (DPI) and nebulizers in pharmacy;
  • production control of active agents;
  • cut-off determination: impactors, cyclones and impingers;
  • atmospheric aerosols: bio-aerosols, stables or composting facilities, nebulized droplets, measurements in street tunnels;
  • fractional separation efficiency determination of filters.
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